ZHOU Ze-wei,WANG De-zhi,SHEN Xiu,et al.Comprehensive Evaluation on Functions & Safety of Imported GM Soybean Using BDI-GS System[J].Soybean Science,2012,31(05):822-826.[doi:10.3969/j.issn.1000-9841.2012.05.029]
用BDI-GS体系综合评价进口转基因大豆的功效与安全
- Title:
- Comprehensive Evaluation on Functions & Safety of Imported GM Soybean Using BDI-GS System
- 文章编号:
- 1000-9841（2012）05-0822-05
- Keywords:
- Benefit-damage index; Genetically modified(GM)soybean; Nutrition and health; Functions and safety
- 分类号:
- R151.2
- 文献标志码:
- A
- 摘要:
- 以低营养玉米饲料建立动物模型，通过已建立的食品BDI-GS评价新体系对进口抗草苷膦转基因大豆的功效安全进行评价。以处于生长期健康的ICR小鼠为研究对象，以单纯玉米饲料喂食小鼠作空白对照组,15%天然大豆及15%转基因大豆制成玉米掺和饲料为受试物实验组，通过13 d喂养，取得小鼠体重、9项脏器组织重量、系数及其BDI和GS等指标，并进行血清生化分析测试作为辅助评价指标。结果显示抗草苷膦转基因大豆喂养条件下，小鼠部分指标的BDI及累计GS明显降低；脏器指标主要表现在胸腺、胰腺和性腺的营养和健康效应上存在显著差异。表明进口RR大豆的营养价值及健康效应方面均明显不如国产天然大豆，存在一定的免疫及内分泌低下等健康隐患。
- Abstract:
- In the present study,an animal model was established by feeding with maize low-nutrient diets,and the imported genetically modified(GM)soybeans was evaluated through the novel BDI-GS system approaches established for functions and safety of food.The growing healthy ICR mice were selected as subject,the control mice were fed simply with maize diet,and the mice subjected test were fed with maize blending 15% conventionally natural soybean and 15% RR soybean.Through the whole duration of 13-day feeding test,obtained mice body weights,9 parameters of organ or tissue weights,indices and its BDI,GS,further analyzed the serum biochemical parameters as adjuvant evidences.The results show that RR soybean may thwart growth performance of test mice,obviously decreased BDI in part parameters and accumulation of general score(GS).The different nutrition and health effects for RR and natural soybean mainly exisxed in organ parameters of thymus,pancreas and spermary.It manifests that imported RR soybean is worse in nutrition value and health functions than that of natural soybean produced in China,with some healthy risks in lowering immune and endocrine function,etc.
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备注/Memo
基金项目：放射所发展基金资助（SF1227）。