[1]贾乃堃 袁其朋.高纯度大豆黄苷及大豆黄素的制备[J].大豆科学,2004,23(01):11-14.[doi:10.11861/j.issn.1000-9841.2004.01.0011]
　Jia Naikun Yuan Qipeng.PREPARATION OF THE HIGH PURITY DAIDZIN AND SAIDZEIN[J].Soybean Science,2004,23(01):11-14.[doi:10.11861/j.issn.1000-9841.2004.01.0011]
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高纯度大豆黄苷及大豆黄素的制备

《大豆科学》[ISSN:1000-9841/CN:23-1227/S] 卷: 第23卷 期数: 2004年01期 页码: 11-14 栏目: 出版日期: 2004-02-25
Title:
PREPARATION OF THE HIGH PURITY DAIDZIN AND SAIDZEIN
文章编号:
1000 -9841(2004)01 -0011 -04
作者:
贾乃堃 袁其朋
北京化工大学制药工程系, 北京100029
Author(s):
Jia Naikun 　Yuan Qipeng
Department of Pharmaceutical Engineering , Beijing University of Chemical Technology , Beijing , 100029
关键词:
大豆异黄酮; 大豆黄苷; 溶剂萃取
Keywords:
Isof lavone ; Daidzin ; Ext raction
分类号:
S 565.138
DOI:
10.11861/j.issn.1000-9841.2004.01.0011
文献标志码:
A
摘要:
使用不同的溶剂从大豆异黄酮粗品中提取大豆黄苷。通过溶剂回流萃取及不同溶剂组合萃取实验确定了最佳的提取条件。结果表明, 丙酮和乙酸乙酯的组合萃取可以将原料中大豆黄苷的含量提高2 .5 倍以上。最终可以得到纯度为90 %的大豆黄苷产品, 收率40 %。产品再通过盐酸水解可以得到其相应甙元。
Abstract:
Daidzin is ext racted f rom roug h isoflavone w ith different solvents .The optimal condition of ex tractionis obtained through the ex periments of the circumfluence ex traction wi th dif ferent solvents and hybrid solvents .The result show s that , on over 2 .5 times content of Daidzin in materials can be arrived w ith the hybridex traction of acetone and ethyl acetate .Ultimately , Daidzin is obtained with a puri ty 90 % and yield 40 %.Andi ts agly cone is attained throug h the hydrolysis of Daidzin wi th hy drochloric acid .

参考文献/References:

1 　Peterson , T .G., Barnes , S .Genistein and biochain A inhibit thegrow th of human prostate cancer cells but not epidermal grow th f actorrecept or ty rosine autophosphorylat ion[ J] .Prostate, 1993 , 22 :335 -345

2 　Messins , M ., Barnes, S .T he role of soy products in reducing cancerrisk[ J] .J .Nat l.Cancer Inst.1991 , 83 :541 -546
3　Aedin Cassidy , Bryn Hanley , Rosa M .Isoflavones , lignans and sti lbenes-origins, metabolism and potential im port ance to human health[ J] .J Sci.Food Agri c, 2000 , 80 :1044 -1047
4　S tephen Barnes .Evolution of the health benefit s of soy isof lavones[ J] .PSEBM , 1998 , 217 :38-42
5　夏剑秋, 刘宇峰.国内外大豆异黄酮的研发及生产动态[ J] .中国油脂, 2000 , 27(5):10 -12
6　史宣明, 岳琳, 武丽荣.大豆异黄酮的提取及精制[ J] .中国油脂,2001 , 26 (2):3 -5
7 　李文亮, 韩继福, 崔洪斌.盐酸水解大豆异黄酮的工艺研究[ J] .食品科学, 2002 , 23 (4) :73 -75

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备注/Memo

作者简介:贾乃(1978 -), 男, 硕士研究生, 主要从事天然产物提取研究。

更新日期/Last Update: 2016-12-31