LU Jia-cheng,SUN Ze-wei,LI Ting-lin.Research Advance on Improving Functional Characteristics of Soybean Antigenic Proteins by Glycosylation[J].Soybean Science,2012,31(03):483-486.[doi:10.3969/j.issn.1000-9841.2012.03.031]
糖基化反应改善大豆抗原蛋白功能特性的研究进展
- Title:
- Research Advance on Improving Functional Characteristics of Soybean Antigenic Proteins by Glycosylation
- 文章编号:
- 1000-9841(2012)03-0483-04
- 分类号:
- S816.4
- 文献标志码:
- A
- 摘要:
- 大豆含有丰富的营养成分,被广泛应用于食品和饲料行业,但大豆中的抗原蛋白对人和动物有一定的致敏作用而不利于吸收和利用,有时甚至导致幼龄动物的死亡。因而改善大豆抗原蛋白功能特性及去除抗原蛋白的致敏性便成为了研究的热点。该文围绕蛋白质糖基化方法可安全有效的改善蛋白质功能性质这一特性,综述了糖基化方法对大豆抗原蛋白功能特性影响的相关研究,以期对大豆抗原蛋白的后续深入研究提供理论参考。
- Abstract:
- Soybean have abundant nutrient factors,and plays an important role in food and feed industry,however,the soybean antigenic proteins can produce allergization effect,sometimes even lead to death of young animals.Improving functional performance of soybean antigenic proteins and inactivating its sensitization have becoming the hot topic.Concentrating on the feature that glycosylation can improve protein function safely and effectively,this article summarized correlation studies about glycosylation effect on functional characteristics of soybean antigenic proteins,so as to offer reference for further study of soybean antigenic proteins.
参考文献/References:
[1]Lalles J P.Nutritional and antinutritional aspects of soyabean and field pea proteins used in veal calf production:A review[J].Livestock Production Science,1993:181-202. [2]Chandra R K.Food hypersensitivity and allergic diseases[J].European Journal of Clinical Nutrition,2002,56:54-56. [3]Herman E M,Helm R M,Jung R,et al.Genetic modification removes an immunodominant allergen from soybean[J].Plant Physiology,2003,132:36-43. [4]Duke W W.Soybean as a possible important source of allergy[J].Allergy,1934,5:300-304. [5]Li D F,Nelssen J L,Reddy P G,et al.Transient hypersensitivity to soybean meal in the early-weaned pig[J].Journal of Animal Science,1990,68:1790-1799. [6]孙泽威,秦贵信,张庆华.大豆抗原蛋白对犊牛生长性能,日粮养分消化率和肠道吸收能力的影响[J].中国畜牧杂志,2005,41(11):30-33.(Sun Z W,Qin G X,Zang Q H.Effects of soybean antigenic protein on growth performance,digestive of diet nutrients and the intestinal absorption ability[J].Chinese Journal of Animal Science,2005,41(11):30-33.) [7]孙泽威,秦贵信,高云航.大豆球蛋白、β-伴大豆球蛋白对反刍前犊牛致敏作用的研究[J].中国畜牧杂志,2006,42(15):38-41.(Sun Z W,Qin G X,Gao Y H.Research of the allergization of glycinin and β-conglycinin on calves that before ruminate[J].2006,42(15):38-41.) [8]Moriyama T,Kishomoto K,Nagai K,et al.Soybean β-conglycinin diet suppresses serum triglyceride levels in normal and genetically obese mice by induction of β-oxidation,down regulation of fatty acid synthase and inhibition of triglyceride absorption[J].Bioscience Biotechnology & Biochemistry,2004,68:352-359. [9]Li D F,Nelssen J L,Reddy P G,et al.Measuring suitability of soybean produets for early-weaned pigs with immunological criteria[J].Journal of Animal Science,1991,69:3299-3307. [10]秦贵信,孙泽威,赵元,等.大豆中主要抗原蛋白的研究进展[J].吉林农业大学学报,2008,30(4):553-558.(Qin G X,Sun Z W,Zhao Y,et al.Research advance in study on allergen proteins in soybean[J].Journal of Jilin Agricultural University,2008,30(4):553-558) [11]金哲,崔成哲,郭晓玉,等.蛋白质的改性技术及应用进展[J].民营科技,2007(9):31.(Jin Z,Cui C Z,Guo X Y,et al.Advances on protein modification technology and application[J].Private Science and Technology,2007(9):31.) [12]姚玉静,杨晓泉,邱礼平,等.食品蛋白质化学改性研究进展[J].粮食与油脂,2006(7):10-12.(Yao Y J,Yang X Q,Qiu L P,et al.Research development chemical modification of food proteins[J].Cereals and Oils,2006(7):10-12.) [13]Castimpoolas N.Isolation of α-,β-,and γ-conglycinins[J].Archives of Biochemistry and Biophysics,1969,129:409-497. [14]黄友如,裘爱泳,华欲飞.大豆蛋白结构与功能关系[J].中国油脂,2004,29(11):24-27.(Huang Y R,Qiu A Y,Hua Y F.The relationship of structure and function of soybean protein[J].China Oils and Fats,2004,29(11):24-27) [15]周瑞宝,周兵.大豆7S和11S球蛋白的结构和功能性质[J].中国粮油学报,1998,13(6):39-42.(Zhou R B,Zhou B.The structure and functional properties of soybean 7S and 11S globulin proteins[J].Jourral of the Chinese Cereals and Oils Association,1998,13(6):39-42.) [16]李丹,崔凯.食品蛋白质的改性技术[J].食品与发酵工业,2000,25(6):58-60.(Li D,Cui K.Modified technology of food protein[J].Food and Fementation Industries,2000,25(6):58-60.) [17]田其英,华欲飞.大豆蛋白溶解性研究[J].粮食与油脂,2006(6):6-8.(Tian Q Y,Hua Y F.Study on the solubility of soybean protein[J].Cereals and Oils,2006(6):6-8) [18]Achouri A,Boye J I,Yaylayan V A,et al.Functional properties of glycated soy 11S glycinin[J].Food Chemistry and Toxicology,2005,70:269-274. [19]苏志光.大豆蛋白的甘露聚糖糖基化研究[D].北京:中国农业大学,2010.(Su Z G.A study of glycosylation of soy protein isolated and mannose[D].Beijing:China Agricultural University,2010.) [20]王晓丹,董学艳,刘继超,等.大麦蛋白湿法糖基化反应研究[J].分子科学学报,2011,27(4):252-257.(Wang X D,Dong X Y,Liu J C,et al.Study of barley protein-glucose graft reaction by wet-heating[J].Journal of Molecular Science,2011,27(4):252-257.) [21]Kato Y,Aoki T,Kato N,et al.Modification of ovalbumin with glucose 6-phosphate by amino-carbonyl reaction:Improvement of protein heat stability and emulsifying activity[J].Journal of Agricultural and Food Chemistry,1995,43(2):301-305. [22]Nakamura S,Ogawa M,Nakai S,et al.Antioxidant activity of a Maillard-type phosvitin-galactomannan conjugate with emulsifying properties and heat stability[J].Journal of Agricultural and Food Chemistry,1998,46:3958-3963. [23]郑喆,卢晶,罗永康.乳清蛋白-葡萄糖的制备及溶解性和热稳定性研究[J].乳业科学与技术,2009(2):55-58.(Zheng Z,Lu J,Luo Y K.Study on preparation and solubility and heat stability of WPI-glucose conjugate[J].Journal of Dairy Science and Technology,2009(2):55-58.)
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备注/Memo
基金项目:国家自然科学基金项目(31072037)。