|Table of Contents|

The Effect of Tea Polyphenols on Oxidative Damage of Pancreas in Mice Induced by Soybean Trypsin Inhibitor(PDF)

《大豆科学》[ISSN:1000-9841/CN:23-1227/S]

Issue:
2018年06期
Page:
950-954
Research Field:
Publishing date:

Info

Title:
The Effect of Tea Polyphenols on Oxidative Damage of Pancreas in Mice Induced by Soybean Trypsin Inhibitor
Author(s):
ZHAO Lin-lin1 HAO Xin1 LI Tong1 MO Lan-yue1 GU Chun-mei2
(1Department of Food Engineering, Boda College of Jilin Normal University,Siping 136000, China; 2Institute of Food Science and Engineering, Jilin Agricultural University, Jilin 130118, China)
Keywords:
Tea polyphenols Soybean trypsin inhibitor Pancreas Serum Free radical Mice
PACS:
-
DOI:
1011861/jissn1000-98412018060950
Abstract:
In order to assess the effect of tea polyphenols on oxidative damage of pancreas in mice induced by soybean trypsin inhibitor factor(STI), 36 male mice were randomly divided into three groups: Control group, model group(STI group, feeding the daily ration of 36 mg·g-1 STI) and tea polyphenols group (TP group, feeding the daily ration of 1000 mg·kg-1 tea polyphenols and 36 mg·g-1 STI) Mice were executed on 21 d and their malonaldehyde(MDA), total antioxidant capacity(T-AOC), several digestive enzyme and hormone contents of pancreas and serum were determined, ultrastructural changes of pancreas were observed by TEM As shown in results, compared with control group, the MDA, somatostatin(SS), amylase(AMS) and lipase(LPS) contents in the pancreas and serum in STI group were significantly increased (P<005) , T-AOC, trypsin(TPS) and insulin(INS) were significantly decreased (P<005), mitochondria were severely damaged In the TP group with the addition of tea polyphenol, the MDA, SS, AMS and LPS contents in the pancreas and serum were significantly decreased (P<005) , T-AOC, TPS and INS were significantly increased (P<005), mitochondria were slightly damaged This study showed that tea polyphenols effectively inhibited the oxidative stress induce by STI, weakened the oxidative damage of pancreas

References:


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Last Update: 2018-12-04