Effects of Genetically Modified Soybeans on Embryonic Development and the Ability of Fertilization in Female Mice(PDF)

¡¶´ó¶¹¿Æѧ¡·[ISSN:1000-9841/CN:23-1227/S]

Issue:

2014Äê04ÆÚ

Page:

578-582

Research Field:

Publishing date:

Info

Title:

Effects of Genetically Modified Soybeans on Embryonic Development and the Ability of Fertilization in Female Mice

Author(s):

LU Chun-bin¹; ZHENG Jian-xin¹; CAI Juan¹; WEI Yang-yang¹; QI Qing-lin¹; LIU Biao²

1.Department of Developmental £¦ Regenerative Biology,Jinan University,Guangzhou 510632,China;

2.Nanjing Institute of Environmental Sciences,Ministry of Environmental Protection,Nanjing 210042,China

Keywords:

Genetically modified soybeans; Estrous cycle; Ability of fertilization; Embryonic development; Reproductive toxicity

PACS:

S565.1

DOI:

10.11861/j.issn.1000-9841.2014.04.0578

Abstract:

The objective of present study was to evaluate the effects of genetically modified soybeans(GM)on embryonic development and the ability of fertilization in female mice.In present study,the female mice were fed genetically modified soybean diet or conventional soybean diet for 90 days,respectively.At 30 and 90 days of feeding trial,the changes of estrous cycle and development of the zygotes,2-cell embryos,blastocysts in mice of two groups were observed.There were no significant differences in estrous cycle,usually varied from 4 to 5 days.Compared with conventional diet,there were no significant differences in the number of zygotes,2-cell embryos,blastocysts,and fertilization rate,as well as the rate of high qualified embryo in female mice fed GM soybean diet.The results of feeding revealed that there were no adverse effects on the estrous cycle and the ability of fertilization,embryonic development of female mice,suggesting no potential reproductive toxicity on female mice fed genetically modified soybeans.

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