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Experimental Study on the Immunity-enhancement Capability of Soybean Minor Peptides in Mice(PDF)

《大豆科学》[ISSN:1000-9841/CN:23-1227/S]

Issue:
2012年03期
Page:
466-469,473
Research Field:
Publishing date:

Info

Title:
Experimental Study on the Immunity-enhancement Capability of Soybean Minor Peptides in Mice
Author(s):
LI Shuo1; CHEN Xuan-qin1; LI Mao-hui2; CHEN Li-mei1; LI Kun-zhi1
1．College of Life Science and Technology，Kunming University of Science and Technology，Kunming 650500，Yunnan；
2．Public Health Inspection Center of Shenyang Medical College，Shenyang 110034，Liaoning，China
Keywords:
Soybean minor peptides; Immunity-enhancement; Mice
PACS:
R151
DOI:
10.3969/j.issn.1000-9841.2012.03.027
Abstract:
To study and investigate the immunity-enhancement capability of soybean minor peptides（Molecular weight 300-700 Da）in mice.The immune indexes were determined after Kunming mice were orally fed soybean minor peptides at 3,6,9(g·kg-1·d-1)doses for consecutive 30 days.The results showed the ability of spleen-lymphocytes transformation and the number of phagocytizing chicken red blood cells in high-dose test groups was significant(P<0.05)higher than the control group.Compared with the control group, there were significant differences of the left and right ear weight and the number of the antibody-producing cells,as well as the antibody numbers in the high and medium dose group(P<0.05).These results demonstrated the soybean minor peptides could significantly stimulate proliferation and transformation of the spleen-lymphocytes;promote delayed type hypersensitivity;raise the quantity of antibody-producing cells and increase the level of blood-serum erythrocytolysin and the phagotrophic function of peritoneal macrophages.However,no significant immunoragulatory effect was found in the activity of NK cells,expurgation effect by mononuclear phagocytes,weight of the mice and their immune organs.In conclusion,the soybean minor peptides had the capability of enhancing immunity.

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Last Update: 2014-08-17