|Table of Contents|

Effect of Soybean Agglutinin （SBA） on Proliferation Function of T and B lymphocytes in Different Species of Animals(PDF)

《大豆科学》[ISSN:1000-9841/CN:23-1227/S]

Issue:
2010年03期
Page:
490-493
Research Field:
Publishing date:

Info

Title:
Effect of Soybean Agglutinin （SBA） on Proliferation Function of T and B lymphocytes in Different Species of Animals
Author(s):
WANG Li-min;  YU Ji;  YANG Shu-bao;  SUN Qing-song;  QIN Gui-xin
College of Animal Science and Technology,Jilin Agricultural University, Changchun 130118, Jilin, China
Keywords:
Soybean agglutinin (SBA); T lymphocyte; B lymphocyte; Proliferation function
PACS:
S815.4
DOI:
10.11861/j.issn.1000-9841.2010.03.0490
Abstract:
T and B lymphocytes from blood of different species of animals were stimulated by purified soybean agglutinin (SBA), and detected through MTT method, while compared with ConA and LPS groups, so the effect of SBA on immune function of different species of animals could be compared. The results showed that the SI of T and B lymphocytes in dog, chicken and rabbit were significantly lower than corresponding ConA and LPS groups（P<0.05）. It was lower in pig and higher in sheep than in control group, but both had no significant difference (P>0.05). The SI of T and B lymphocytes stimulated by SBA in different species of animals were different，and the dominant feature was that chicken were the highest and sheep were the lowest. In the same species of animals, the effects of proliferation function of T and B lymphocytes were different, the SI of T lymphocytes were higher than that of B lymphocytes in rabbit, dog, and pig, but it was just against in sheep and chicken. These results indicated that the effects of proliferation function of T and B lymphocytes stimulated by SBA in different species of animals exist, especially in dog, rabbit and chicken. Except sheep, the proliferation function of T and B lymphocytes from other species of animals were more or less inhibited. It showed that the immunocytes from different species of animals have different glycosylation mode, cytodifferentiation process and signal transmission mechanism.

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Last Update: 2014-09-14