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STUDY ON PREPARATION OF VITAMIN C LIPOSOME(PDF)

《大豆科学》[ISSN:1000-9841/CN:23-1227/S]

Issue:
2007年02期
Page:
270-272
Research Field:
Publishing date:

Info

Title:
STUDY ON PREPARATION OF VITAMIN C LIPOSOME
Author(s):
LIU Ya-wen;  CAO Guang-qun;  CHEN Ting-ting
School of Chemical and Material Engineering，Southern Yangtze University，Wuxi 214036
Keywords:
Vitamin C; Liposome; Film dispersion method; Entrapment efficiency
PACS:
TS224.4
DOI:
10.3969/j.issn.1000-9841.2007.02.031
Abstract:
To optimize the preparation formulation of vitamin C liposomes,the liposomes were prepared by film dispersion-ultrasonic emulsify method,taking entrapment efficiency as index,and designing an orthogonal experiment.The optimal formulation were: phosphatidylcholine / cholesterin / vitamin E (molar ratio)4∶2∶0.34;vitamin C concentration:3.3 mg/mL;PBS buffer pH value:7.93;chloroform for film forming :30 mL.Under the formulation the entrapment efficiency was 58.32%.The structure of liposome was observed under the scan electronic microscope.The main diameter of the liposome particles was 310 nm.

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Last Update: 2014-10-22